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Novo Nordisk Acquires Prothena’s ATTR Program in $1.2B Deal

To develop the Phase 2 ready antibody PRX004 for the rare heart disease ATTR cardiomyopathy.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Prothena Corp. and Novo Nordisk entered into a definitive purchase agreement under which Novo Nordisk has acquired Prothena’s clinical stage antibody PRX004 and broader ATTR amyloidosis program for as much as $1.2 billion, including $100 million in upfront and near-term clinical milestones. PRX004 is a phase 2-ready anti-amyloid immunotherapy designed to deplete the amyloid deposits that are associated with the disease pathology of ATTR amyloidosis. ATTR amyloidosis is a rare, progressive ...

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